Primate profiles
نویسندگان
چکیده
منابع مشابه
Pedigreed primate embryonic stem cells express homogeneous familial gene profiles.
Human embryonic stem cells (hESCs) hold great biomedical promise, but experiments comparing them produce heterogeneous results, raising concerns regarding their reliability and utility, although these variations may result from their disparate and anonymous origins. To determine whether primate ESCs have intrinsic biological limitations compared with mouse ESCs, we examined expression profiles ...
متن کاملRegulatory element copy number differences shape primate expression profiles.
Gene expression differences are shaped by selective pressures and contribute to phenotypic differences between species. We identified 964 copy number differences (CNDs) of conserved sequences across three primate species and examined their potential effects on gene expression profiles. Samples with copy number different genes had significantly different expression than samples with neutral copy...
متن کاملComparison of non-human primate and human whole blood tissue gene expression profiles.
Gene expression profiling is an important tool in the development of medical countermeasures against chemical warfare agents (CWAs). Non-human primates (NHPs), specifically the rhesus macaque (Macaca mulatta), the cynomologus macaque (Macaca fascicularis), and the African green monkey (Chlorocebus aethiops), are vital models in the development of CWA prophylactics, therapeutics, and diagnostics...
متن کاملExpression Profiles of Vpx/Vpr Proteins Are Co-related with the Primate Lentiviral Lineage
Viruses of human immunodeficiency virus type 2 (HIV-2) and some simian immunodeficiency virus (SIV) lineages carry a unique accessory protein called Vpx. Vpx is essential or critical for viral replication in natural target cells such as macrophages and T lymphocytes. We have previously shown that a poly-proline motif (PPM) located at the C-terminal region of Vpx is required for its efficient ex...
متن کاملProfiles of Motor Unit Activity Generated by a Recurrent Ann of the Primate Premotoneuronal Circuitry
A dynamic recurrent neural network composed of units with continuous activation functions were derived to simulate motoneuronal activity profiles generating bidirectional wrist movements in the monkey. The model incorporates anatomical connections of premotor neurons, i.e. neurons projecting monosynaptically to spinal motoneurons, including cortical and rubral neurons, muscle afferents and segm...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Nature
سال: 1984
ISSN: 0028-0836,1476-4687
DOI: 10.1038/312676a0